WHAT I WRITE NOW WILL BE ADOPTED BY SOME SCIENTIST AND HE WILL CLAIM NOBEL PRIZE A DECADE FROM NOW..
ALL ARE WONDERING WHY THERE IS A SUDDEN SPURT IN METASTATIC CANCER..
IF YOU ARE NOT A HALF WIT, THE ANSWER IS SIMPLE— SOME NEW ITEM WHICH HAS BEEN IMPOSED ON THE HUMAN POPULATION LIVING IN MODERN CITIES.
Epithelial-to-mesenchymal transition (EMT) is the initial step enabling the metastasis of cancer cells, which leads to death..
EMT is a process by which cells attain migratory and invasive properties, eventually leading to cancer metastasis. It is activated by tumour microenvironment that enhance tumour procession
EMT refers to a process where an established epithelium either "delaminates" allowing cells to leave the epithelium and become connective tissue (mesenchymal) in organisation. This transition can be a permanent change, where the mesenchymal cells may reestablish a new epithelial organization..
Epithelial cells (organised cellular layer) which loose their organisation and migrate/proliferate as a mesenchymal cells (disorganised cellular layers) are said to have undergone an Epithelial Mesenchymal Transition (EMT).
Mesenchymal cells, connective tissue-like, that have undergone this process may at a later time and under specific signaling can undergo the opposite process, mesenchyme to epithelia.
Inside the nucleus of a cell, our genes are arranged along twisted, double-stranded molecules of DNA called chromosomes. At the ends of the chromosomes are stretches of DNA called telomeres, which protect our genetic data, make it possible for cells to divide, and hold some secrets to how we age and get cancer.
Telomeres have been compared with the plastic tips on shoelaces, because they keep chromosome ends from fraying and sticking to each other, which would destroy or scramble an organism's genetic information.
Yet, each time a cell divides, the telomeres get shorter. When they get too short, the cell can no longer divide; it becomes inactive or "senescent" or it dies. This shortening process is associated with aging, cancer, and a higher risk of death. So telomeres also have been compared with a bomb fuse.
Telomeres allow cells to divide without losing genes. Cell division is necessary for growing new skin, blood, bone, and other cells.
Because broken DNA is dangerous, a cell has the ability to sense and repair chromosome damage. Without telomeres, the ends of chromosomes would look like broken DNA, and the cell would try to fix something that wasn't broken. That also would make them stop dividing and eventually die.
Before a cell can divide, it makes copies of its chromosomes so that both new cells will have identical genetic material. To be copied, a chromosome's two DNA strands must unwind and separate. An enzyme (DNA polymerase) then reads the existing strands to build two new strands.
It begins the process with the help of short pieces of RNA. When each new matching strand is complete, it is a bit shorter than the original strand because of the room needed at the end for this small piece of RNA.
It is like someone who paints himself into a corner and cannot paint the corner.
An enzyme named telomerase adds bases to the ends of telomeres. In young cells, telomerase keeps telomeres from wearing down too much. But as cells divide repeatedly, there is not enough telomerase, so the telomeres grow shorter and the cells age.
Telomerase remains active in sperm and eggs, which are passed from one generation to the next. If reproductive cells did not have telomerase to maintain the length of their telomeres, any organism with such cells would soon go extinct.
As a cell begins to become cancerous, it divides more often, and its telomeres become very short. Many cancers have shortened telomeres, including pancreatic, bone, prostate, bladder, lung, kidney, and head and neck.
Measuring telomerase is a way to detect cancer.
SO WHEN THE POST BELOW IS SENT TO THE HEALTH MINISTRY—WHAT DO THEY DO?
SOME DHAKKAN WHO DOES NOT KNOW IF HE IS COMING OR GOING ( WITHOUT PEERING INTO HIS TIFFIN BOX ) WILL GOOGLE , A KEY WORD , SCAN THE POSTS OF THE FIRST PAGE—AND DECLARE , THERE IS NO SUCH THING CALLED CANCER DUE TO NANO PARTICLES..
A 68-year-old has twice the chance of dying within a year compared with a 61-year-old. – short telomere party get Alzheimer disease, hardening of the arteries, high blood pressure, type 2 diabetes, cancers of prostrate etc
IF YOU CAN PREVENT YOUR TELOMERS FROM SHORTENING YOU CAN CHALLENGE ALL TO A 25 KG DUMB BELL CONTEST AND WIN..
HUMAN DNA DEGRADED FROM 12 STRAND NIL JUNK ( MAHARISHIS ) TO 2 STRAND 97% JUNK--
KING LEMON SIZED PINEAL GLAND OF MAHARISHIS BECAME CALCIFIED DRIED UP RAISIN TYPES – THERE IS A REASON.
ANCIENT MAHARISHIS HAD A 300 YEAR LIFE SPAN – WHY ?
EVIL PHARMA HAS USED DEEP STATE AND CONDEMNED CANNABIS ( TELOMERE MAINTAINING ) , WHICH IS NOT ADDICTIVE..
HERE IS MY FOURTH DIKSHA TO MY READERS ..
WARNING: PEOPLE WHO DENIGRATE CAPT AJIT VADAKAYIL MUST NOT USE IT. THEIR LIVES WILL BE CUT SHORT.
WRITE THE NUMBER BELOW ON ANY PART OF YOUR CONVENIENT BODY COVERED BY CLOTHES..
IT IS A DIGITALISED MANTRA ( ISOTOPE MAGIC ) FOR REJUVENATING YOUR TELOMERES
987 258 793 68
MAINTAIN YOUR TELOMERE LENGTH WITH SURYA NAMASKAR
ELIMINATE ALL PROCESSED FOOD FROM YOUR DIET..
BELOW: ALKA YAJNIKs FATHER CAPT YAJNIK WAS A HOOGLY RIVER PILOT.. HE ONCE GAVE ME HER CASSETTE TAPE--SHE WAS A SMALL CHILD AND SHE WAS GOOD.
MY FRIEND WAS HER NEXT DOOR NEIGHBOUR AND ONCE WE PEEPED OVER THE FENCE-- SHE COULD HAVE BEEN SAY 13..
CAPT AJIT VADAKAYIL